Patent · US Active

Target cell concentration using dielectrophoresis (DEP)

US10710075B2 · kind B2 · utility

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Key dates

Filing dateJun 20, 2017
Grant dateJul 14, 2020
Priority date
Expiry dateJun 20, 2037

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N2001/4038
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

Methods and devices for concentrating target cells using dielectrophoresis (DEP) are disclosed. The method allows relatively high throughput of sample through a microfluidic device in order to allow rapid capture of target cells even when they are present in low concentrations within the sample. The method utilizes multiple chambers through which samples will flow, the chambers arranged such that the first capture area has a larger area and faster flow rate than a second chamber, the second chamber being positioned downstream of the first capture area and being smaller with a slower flow rate to further concentrate the material captured in the first capture area.

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