Tricyclic sulfones as RORγ modulators
US10711020B2 · kind B2 · utility
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Key dates
| Filing date | Mar 7, 2019 |
| Grant date | Jul 14, 2020 |
| Priority date | — |
| Expiry date | Mar 7, 2039 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D495/08
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
There are described RORγ modulators of the formula (I), and formula (II) or stereoisomers, tautomers, pharmaceutically acceptable salts, solvates, or prodrugs thereof, wherein all substituents are defined herein. Also provided are pharmaceutical compositions comprising the same. Such compounds and compositions are useful in methods for modulating RORγ activity in a cell and methods for treating a subject suffering from a disease or disorder in which the subject would therapeutically benefit from modulation of RORγ activity, for example, autoimmune and/or inflammatory disorders.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.