Steroid analogues for neuroprotection
US10716795B2 · kind B2 · utility
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4Claims
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Key dates
| Filing date | Apr 4, 2018 |
| Grant date | Jul 21, 2020 |
| Priority date | — |
| Expiry date | Apr 4, 2038 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07J75/005
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided are steroid analogues functionalized with polar substituents at the C3 and/or C20 positions of the steroid ring system that exhibit improved water solubility. Also provided are pharmaceutical compositions comprising the steroid analogues and methods using the novel steroid analogues for the treatment and prevention of neurodegeneration in a patient following injury to the central nervous system.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.