Use of P97 as an enzyme delivery system for the delivery of therapeutic lysosomal enzymes
US10716862B2 · kind B2 · utility
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3Claims
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Key dates
| Filing date | Feb 28, 2017 |
| Grant date | Jul 21, 2020 |
| Priority date | — |
| Expiry date | Feb 28, 2037 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/566
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention provides for compositions and methods for treating, ameliorating or preventing a lysosomal storage disease by administering to a patient suffering front a lysosomal storage disease a P97 conjugated with an enzyme which is capable of transportation into the lysosomes of cells on either sides of the blood brain barrier.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.