Mammalian cell culture-produced neublastin antibodies

US10717965B2 · kind B2 · utility

Assignee

• Gloriana Therapeutics · US

Inventors

• Alan Gilbert · Cambridge, US
• Kyle McElearney · Medford, US
• Terrence Michael Dobrowsky · Cambridge, US
• Rashmi Rohit Kshirsagar · Ashland, US

Key dates

• Filing date: Dec 21, 2018
• Grant date: Jul 21, 2020
• Expiry date: Dec 21, 2038

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2511/00
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

The present disclosure pertains to a mammalian cell culture genetically modified to express, and which expresses, a neublastin antibody polypeptide, or fragment thereof, in the culture, and to a neublastin antibody polypeptide, or fragment thereof, made by a mammalian cell culture genetically modified to express, and which expresses, the neublastin antibody polypeptide, or fragment thereof.