Patent · US Active

Fluorescent probes for abasic site detection

US10718028B2 · kind B2 · utility

0Cited by

1References

12Claims

0Family size

Assignee

CASE WESTERN RESERVE UNIVERSITY · US

Inventors

Stanton Gerson · Hunting Valley, US
Yanming Wang · Beachwood, US
Allison G. Condie · Cleveland, US

Key dates

Filing date	Apr 14, 2016
Grant date	Jul 21, 2020
Priority date	—
Expiry date	Oct 7, 2036

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Q2600/136
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

A fluorescent probe for binding to and detection of AP sites of DNA includes the following formula: F-L-X where F is a fluorescent moiety, X is an aminooxy group (—ONH2), and L is a linker that links or couples the fluorescent moiety to the oxyamine.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.