Method for preparation of highly polarized nuclear spins containing samples and uses thereof for NMR and MRI
US10718840B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Jun 26, 2016 |
| Grant date | Jul 21, 2020 |
| Priority date | — |
| Expiry date | Jun 26, 2036 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01R33/4806
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method for the preparation of a highly polarized nuclear spins containing sample of an organic or inorganic material, containing H or OH groups or adsorbed water molecules. Such highly polarized nuclear spins containing samples can be subjected to nuclear magnetic resonance (NMR) measurement and/or can be thawed and immediately administered to an individual undergoing a magnetic resonance imaging (MRI) scan. The method is based on generating unstable radicals on the surface of the sample in the presence of ionized environment followed by cooling the sample to cryogenic temperatures. A device for carrying out a particular step of said method is also discloses.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.