Patent · US Active

EDDS chelated nanoceria with catalase-like activity

US10722474B2 · kind B2 · utility

1Cited by
6References
6Claims
0Family size

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Key dates

Filing dateJan 20, 2016
Grant dateJul 28, 2020
Priority date—
Expiry dateJan 20, 2036

Classification

  • Technology area (CPC F)Mechanical Engineering; Lighting; Heating
  • CPC primaryF41C33/041
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

A process for making nanoparticles of biocompatible materials is described, wherein an aqueous reaction mixture comprising cerous ion, ethylenediaminedisuccinic acid, an oxidant, water, and optionally citric acid, is provided along with temperature conditions to directly form within the reaction mixture, a stable dispersion of cerium oxide nanoparticles. Biocompatible, nanoparticles comprised of cerium oxide, ethylenediaminedisuccinic acid, and optionally citric acid, are described. An increase in catalase-like enzyme activity is demonstrated by cerium oxide nanoparticles prepared with citric acid and ethylenediaminedisuccinic acid.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.