Glutaminase inhibitor therapy
US10722487B2 · kind B2 · utility
9Cited by
8References
35Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 18, 2018 |
| Grant date | Jul 28, 2020 |
| Priority date | — |
| Expiry date | Oct 18, 2038 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K51/0408
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed herein are methods of treating a tumor or cancer in a subject whose tumor or cancer cells express low levels of asparagine synthetase (ASNS), and compounds and compositions useful in such treatment. Also disclosed herein are methods of evaluating whether to administer a compound that inhibits glutathione production or a glutaminase inhibitor to a subject with a tumor or cancer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.