Gossypol 7-N-isatin Schiff base compounds with antitumor activities and a method of preparing the same

US10722500B2 · kind B2 · utility

Assignee

• SHAANXI PANLONG PHARMACEUTICAL GROUP LIMITED BY SHARE LTD. · CN

Inventors

• Xiaolin Xie · Xi'an, CN
• Dezhu Zhang · Xi'an, CN
• Shunjun Ding · Xi'an, CN
• Chengyuan Liang · Xi'an, CN

Key dates

• Filing date: Feb 7, 2019
• Grant date: Jul 28, 2020
• Expiry date: Mar 30, 2039

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N33/5011
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A gossypol 7-N-isatin Schiff base compounds compound with antitumor activities represented by formula I: is disclosed. In formula I, R is hydrogen, alkyl, cycloalkyl, alkoxy, unsubstituted or substituted phenyl, or substituted or substituted benzyl. A method of preparing the compound of formula I is also disclosed.