Methods of diagnosing and treating cancer
US10722530B2 · kind B2 · utility
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Key dates
| Filing date | Dec 26, 2017 |
| Grant date | Jul 28, 2020 |
| Priority date | — |
| Expiry date | Jul 14, 2038 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P35/02
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method of treating cancer in a subject includes determining the p53 status and the level of UDG in cancer cells of the subject and administering an antimetabolite agent in combination with an AP endonuclease inhibitor or UDG inhibitor if the determined level of UDG in the cancer cells is increased relative to the control level and the cancer cells are p53 mutant or deficient cancer cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.