Methods of reducing excitotoxicity-induced retinal ganglionic neuron degeneration by an orthodenticle HOMOLOG2 (OTX2) homeoprotein
US10722554B2 · kind B2 · utility
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8Claims
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Key dates
| Filing date | Jan 9, 2009 |
| Grant date | Jul 28, 2020 |
| Priority date | — |
| Expiry date | Sep 16, 2031 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A90/10
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to the use of a homeoprotein of the bicoid family, in particular of the Otx family, for enhancing the survival of cultivated retinal ganglion neurones, and for preventing or treating ganglion neuron degeneration particularly occurring in glaucoma.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.