Patent · US Active

Methods for treating GI syndrome and graft versus host disease

US10722577B2 · kind B2 · utility

0Cited by
6References
9Claims
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Assignee

Inventors

Key dates

Filing dateMay 28, 2013
Grant dateJul 28, 2020
Priority date—
Expiry dateMar 25, 2034

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07K2317/76
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

It has been discovered that administering therapeutically effective amounts of an antibiotic that kills Gram-negative bacteria, together with an anti-ceramide antibody or anti-ceramide mimetic, treats and prevents an array of diseases mediated by cytolytic T lymphocyte (CTL)-induced killing and/or by damage to endothelial microvasculature, including Radiation GI syndrome, GvHD disease, inflammatory diseases and autoimmune diseases.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.