Patent · US Active

Tubulysin analogs and methods for their preparation

US10723727B2 · kind B2 · utility

0Cited by

8References

7Claims

0Family size

Assignee

PFIZER INC. · US

Inventors

Chakrapani Subramanyam · South Glastonbury, US
Lawrence Nathan Tumey · Fairview Park, US
Longfei Xie · Groton, US
Carolyn Leverett · Groton, US
Beth Vetelino · Preston, US
Sai Chetan K. Sukuru · Glastonbury, US
Sarah Hudson · Limerick, IE
Venkata Ramana Doppalapudi · San Diego, US
Abhijit Suresh Bhat · Cambridge, US

Key dates

Filing date	Jan 27, 2017
Grant date	Jul 28, 2020
Priority date	—
Expiry date	Jan 27, 2037

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D277/56
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention is directed to novel cytotoxic tubulysin analogs and derivatives, to antibody drug conjugates thereof, and to methods for using the same to treat medical conditions including cancer.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.