Solid forms of a selective CDK4/6 inhibitor
US10723730B2 · kind B2 · utility
1Cited by
6References
21Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 9, 2017 |
| Grant date | Jul 28, 2020 |
| Priority date | — |
| Expiry date | Nov 9, 2037 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P35/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
This invention relates to the crystalline free base of acetyl-8-cyclopentyl-5-methyl-2-(5-piperazin-1-yl-pyridin-2-ylamino)-8H-pyrido[2,3-d]pyrimidin-7-one, formula (1) having improved properties, to pharmaceutical compositions and dosage forms comprising the free base, and to methods for making and using such compounds, compositions and dosage forms in the treatment of cell proliferative diseases, such as cancer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.