Homogeneous polysaccharide with immunoregulation activity and preparation method thereof
US10723811B2 · kind B2 · utility
Assignee
Inventor
Key dates
| Filing date | Apr 3, 2018 |
| Grant date | Jul 28, 2020 |
| Priority date | — |
| Expiry date | Jul 13, 2038 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07B2200/07
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a homogeneous polysaccharide with an immunoregulation activity and a preparation method thereof. The homogeneous polysaccharide with the immunoregulation activity is a single chromatographic peak and has a molecular weight of 6880±50 Da and an optical rotation value of 158.4±0.5°. An infrared spectrum has an α-configuration sugar characteristic absorption peak at 847.6 cm−1. Hydrogen-proton characteristic chemical shifts in hydrogen spectra of the polysaccharide are δ 5.40, 3.95, 3.84 and 3.61. Carbon signal characteristic chemical shifts in carbon spectra are δ 99.6, 76.6, 73.3, 71.5, 71.1 and 60.4. The homogeneous polysaccharide has an effect of enhancing body immunity, can achieve excellent anti-tumor, antiviral and anti-infection effects and the like in regulation of immunity-related diseases, and has potential development values in drug and health care product industries for treatment and prevention of the diseases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.