Patent · US Active

Application of ethyl p-methoxycinnamate and derivatives thereof in maintaining self-renewal and pluripotency of stem cells

US10723998B2 · kind B2 · utility

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6Claims

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Assignee

Northeast Normal University · CN

Inventors

Yongli Bao · Jilin, CN
Yuxin Li · Freeport, US
Hongshuang Qin · Jilin, CN

Key dates

Filing date	May 5, 2015
Grant date	Jul 28, 2020
Priority date	—
Expiry date	May 5, 2035

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2501/999
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Disclosed is a use of ethyl p-methoxycinnamate and derivatives thereof in preparing drugs, culture media, regulating agents or cosmetic and skin caring products for maintaining self-renewal and pluripotency of stem cells. The stem cells comprise adult stem cells, embryonic stem cells and induced pluripotent stem (iPS) cells. Also disclosed is a use of ethyl p-methoxycinnamate and the derivatives thereof in in-vitro amplification of stem cells and preparation of induced pluripotent stem (iPS) cells and a use of ethyl p-methoxycinnamate and the derivatives thereof in preparing drugs for treating cell deletion or injury diseases.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.