Methods for obtaining regulatory T cells and uses thereof
US10724001B2 · kind B2 · utility
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12Claims
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Key dates
| Filing date | Jul 1, 2016 |
| Grant date | Jul 28, 2020 |
| Priority date | — |
| Expiry date | Oct 17, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2502/1157
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed is a method for obtaining a population of human Treg cells including the steps of: (a) culturing a population of human monocytes with a medium including an amount of an interleukin-34 (IL-34) polypeptide in order to obtain a population of immunosuppressive macrophages; (b) co-culturing a population of human peripheral blood mononuclear cells (PBMCs) and the population of immunosuppressive macrophages obtained at step (a).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.