Stabilisation of biological samples

US10724074B2 · kind B2 · utility

Assignee

• QIAGEN GmbH · DE

Inventors

• Martin Horlitz · Hilden, DE
• Annabelle Schubert · Hilden, DE
• Markus Sprenger-Haussels · Mettmann, DE
• Kalle Günther · Hilden, DE
• Ralf Wyrich · Grevenbroich, DE
• Uwe Oelmüller · Erkrath, DE

Key dates

• Filing date: Sep 25, 2013
• Grant date: Jul 28, 2020
• Expiry date: Feb 20, 2035

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N15/1003
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

The present invention provides methods, compositions and devices for stabilizing the extracellular nucleic acid population in a cell-containing biological sample and for stabilizing the transcriptome of contained cells.