Functionalized magnetic nanoparticles and a method for preparation thereof
US10726981B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Sep 21, 2016 |
| Grant date | Jul 28, 2020 |
| Priority date | — |
| Expiry date | Jun 27, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC22C2202/02
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
The present disclosure relates to a method for manufacturing a covalently functionalized coated magnetic nanoparticle and to said particles and uses thereof. The preparation method includes forming a shell of a hydrophilic polymer coating layer on top of a magnetic metal core coated with a carbon coating. In the method a particle comprising a magnetic metal core coated with a carbon coating is provided. The surface of the particle is subjected to covalent functionalization by generating amino reactive groups via diazonium chemistry and subsequently an irreversible attachment of an atom transfer radical polymerization (ATRP) initiator is carried out on said surface. A hydrophilic polymer layer is formed) by a surface initiated atom transfer radical polymerization (SI-ATRP) reaction with a monomer comprising N-isopropylacrylamide (NIPAM).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.