Ketobutyrate compounds and compositions for treating age-related symptoms and diseases

US10729668B2 · kind B2 · utility

Assignee

• The Regents of the University of California · US

Inventors

• Jing Huang · New Taipei, TW
• Randall M. Chin · San Fernando, US
• Xudong Fu · Los Angeles, US
• Heejun Hwang · Los Angeles, US
• Karen Reue · Torrance, US
• Laurent Vergnes · Los Angeles, US
• Meisheng Jiang · Los Angeles, US
• Brett E. Lomenick · Los Angeles, US
• Xiang Yin · Los Angeles, US
• Mansoureh Eghbali · Los Angeles, US
• Jingyuan Li · San Diego, US
• Samuel Wheeler French · Los Angeles, US
• Ronik Khachatoorian · Los Angeles, US

Key dates

• Filing date: Jun 29, 2015
• Grant date: Aug 4, 2020
• Expiry date: Jun 29, 2035

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Disclosed herein are methods for (a) treating, inhibiting, or reducing aging of a subject, (b) treating, inhibiting, or reducing an age-related symptom or an age-related disease in a subject, and/or (c) increasing the lifespan of a subject which comprise administering to the subject one or more ketobutyrate compounds and compositions thereof.