Taxane particles and their use

US10729673B2 · kind B2 · utility

Assignee

• CRITITECH, INC. · US

Inventors

• Michael Baltezor · Lee's Summit, US
• Joseph FARTHING · Lawrence, US
• Jake SITTENAUER · Lawrence, US
• Jahna ESPINOSA · Lawrence, US
• Samuel Campbell · Richmond, US
• Matthew McClorey · Lawrence, US
• Julia K. FISCHER · Lawrence, US
• Mark Williams · Richland, US
• Gary E. CLAPP · Lawrence, US

Key dates

• Filing date: Jan 30, 2020
• Grant date: Aug 4, 2020
• Expiry date: Jan 30, 2040

Classification

• Technology area (CPC B): Performing Operations; Transporting
• CPC primary: B05D2401/90
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Compositions are provided that include having at least 95% by weight of a taxane, or a pharmaceutically acceptable salt thereof, where the particles have a mean bulk density between about 0.050 g/cm3 and about 0.15 g/cm3, and/or a specific surface area (SSA) of at least 18 m2/g, 20 m2/g, 25 m2/g, 30 m2/g, 32 m2/g, 34 m2/g, or 35 m2/g. Methods for making and using such compositions are also provided.