Gossypol isatin schiff base compounds with antitumor activities and a method of preparing the same

US10729675B2 · kind B2 · utility

Assignee

• SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY · CN

Inventors

• Chengyuan Liang · Xi'an, CN
• Xingke Ju · Xi'an, CN
• Shunjun Ding · Xi'an, CN
• Lei Tian · Batou, CN
• Yuzhi Liu · Xi'an, CN
• Xiaolin Xie · Xi'an, CN
• Dezhu Zhang · Xi'an, CN
• Wenbo Yao · Xi'an, CN
• Dan Yang · Wuxi, CN

Key dates

• Filing date: Feb 7, 2019
• Grant date: Aug 4, 2020
• Expiry date: Apr 4, 2039

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N33/5011
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A gossypol isatin Schiff base compound with antitumor activities represented by formula I: R1 and R2 are independently hydrogen, alkyl, cycloalkyl, alkoxy, nitro, halogen, unsubstituted or substituted phenyl, or unsubstituted or substituted benzyl. A method of preparing the compound of formula I is also disclosed.