Patent · US Active

ISCOM preparation and use thereof

US10729764B2 · kind B2 · utility

10Cited by

8References

26Claims

0Family size

Assignee

Novavax AB · SE

Inventors

Bror Morein · Uppsala, SE
Karin Lövgren Bengtsson · Uppsala, SE

Key dates

Filing date	Dec 31, 2014
Grant date	Aug 4, 2020
Priority date	—
Expiry date	May 1, 2038

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K2039/55577
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention relates to a composition comprising a mixture of at least two iscom complexes each complex comprising essentially one saponin fraction from Quillaja Saponaria Molina. The complexes may be iscom complexes or iscom matrix complexes. The invention also pertains to the use of such a mixture for the preparation of an immunomodulating pharmaceutical, and adjuvant, formulations for immunization, e.g. for production of monoclonal antibodies, and a vaccine. Kits of parts comprising at least two parts, wherein each part comprises one iscom complex or one iscom matrix complex according to the invention are also embraced.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.