Process for the separation of organic compounds
US10730022B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Dec 16, 2016 |
| Grant date | Aug 4, 2020 |
| Priority date | — |
| Expiry date | Jan 19, 2037 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01D2325/38
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
A membrane based process separates amines or organic acids from a solution containing at least one amine or at least one organic acid according to their hydrophobic properties. The more hydrophobic amine or organic acid passes the hydrophobic membrane into an acidic aqueous solution, thus selectively removing the amine or organic acid from the first solution. The process is particularly suitable to obtain chiral amines in high yield. A transaminase-catalyzed transamination of an amino donor and amino acceptor is combined with a hydrophobic membrane separation of the produced chiral amine. The selective removal of the chiral amine from the reaction mixture promotes the further transformation of the amino acceptor into the product chiral amine.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.