Compound containing tricyclic heteroaryl group
US10730887B2 · kind B2 · utility
1Cited by
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17Claims
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Key dates
| Filing date | Dec 12, 2017 |
| Grant date | Aug 4, 2020 |
| Priority date | — |
| Expiry date | Dec 12, 2037 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/55
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A class of compounds containing a tricyclic heteroaryl group is provided. Specifically, a compound of the structure represented by the following formula (I) (each group is as defined in the specification), a pharmaceutical composition containing the compound of the formula (I), and their isotope derivatives, chiral isomers, allosterics, different salts, prodrugs, preparations, etc, are provided. It can effectively inhibit protein kinases (such as EGFR, FAK, SYK, FLT-3, Axl, CDK, JAK, etc.), thereby treating various tumors, non-alcoholic liver disease (NASH), pulmonary fibrosis (IPF), and related variety of diseases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.