Patent · US Active

Dendrimer-drug conjugates

US10730999B2 · kind B2 · utility

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32Claims
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Assignee

Inventors

Key dates

Filing dateJun 5, 2015
Grant dateAug 4, 2020
Priority date
Expiry dateJun 5, 2035

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC08L101/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention generally relates to macromolecules of dendrimer-drug conjugates. In particular, the invention relates to macromolecules comprising a pharmaceutically active agent, such as a protein or peptide, attached to a core of a dendrimer derived from branched building units, such as lysine or lysine analogues. The invention also relates to the synthesis of the dendrimers and macromolecules, and the use of such macromolecules, particularly in therapeutic applications, and pharmaceutical compositions comprising them.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.