Methods and compositions for stabilizing trans-splicing intein modified proteases
US10731143B2 · kind B2 · utility
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Key dates
| Filing date | Oct 28, 2015 |
| Grant date | Aug 4, 2020 |
| Priority date | — |
| Expiry date | Feb 1, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/92
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Methods for producing a trans-splicing intein-modified protease with enhanced solubility and regulating its activity are described. Intein-modified proteases having enhanced solubility and polynucleotides encoding the same are provided. Methods of storing trans-splicing proteases are also described.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.