Diagnostic transcript and splice patterns of HR-HPV in different cervical lesions

US10731228B2 · kind B2 · utility

Assignee

• Deutsches Krebsforschungszentrum · DE

Inventors

• Markus Schmitt · Neubiberg, DE
• Lutz Gissmann · Wiesloch, DE
• Michael Pawlita · Eschelbronn, DE
• Daniela Hoefler · Heidelberg, DE

Key dates

• Filing date: Oct 19, 2017
• Grant date: Aug 4, 2020
• Expiry date: Oct 19, 2037

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12Q1/6883
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

The present invention relates to a method for differentiating in a subject with HR-HPV between a severe form of HR-HPV infection and a mild form of HR-HPV infection. It further is concerned with a composition comprising a probe oligonucleotide mixture, a device, and a kit for use in conjunction with the method of the invention.