Patent · US Active

Neuromodulation and associated systems and methods for the treatment of cancer

US10736692B2 · kind B2 · utility

3Cited by
88References
27Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 27, 2016
Grant dateAug 11, 2020
Priority date
Expiry dateJun 11, 2038

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61N2007/0043
  • WIPO fieldMedical technology
  • WIPO sectorInstruments

Abstract

Methods for treating a human patient diagnosed with cancer with therapeutic neuromodulation and associated systems are disclosed herein. Sympathetic nerve activity can contribute to several cellular and physiological processes associated with the progression of cancer. One aspect of the present technology is directed to methods that attenuate neural traffic along target sympathetic nerves innervating tissue proximate a primary malignant tumor. Other aspects are directed to methods that at least partially inhibit sympathetic neural activity in a renal nerve of a patient diagnosed with cancer or who has a high risk of developing cancer. Targeted sympathetic nerve activity can be attenuated to improve a measurable physiological parameter corresponding to the progression of cancer in the patient. The attenuation can be achieved, for example, using an intravascularly positioned catheter carrying a therapeutic assembly, e.g., a therapeutic assembly configured to use electrically-induced, thermally-induced, and/or chemically-induced approaches to modulate the target sympathetic nerve.

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