Methods of inhibiting cataracts and presbyopia
US10736863B2 · kind B2 · utility
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5Claims
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Key dates
| Filing date | Nov 11, 2016 |
| Grant date | Aug 11, 2020 |
| Priority date | — |
| Expiry date | Nov 11, 2036 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG02C7/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Described herein are methods of inhibiting or reversing the progression of cataract formation or presbyopia in an eye by administering a bifunctional molecule comprising a substituted or unsubstituted amine, succinimide, carboxylic acid, isocyanate, isothiocyanate, sulfonyl chloride, aldehyde, carbodiimide, acyl azide, anhydride, fluorobenzene, carbonate, N-hydroxysuccinimide ester, imidoester, epoxide or fluorophenyl ester covalently linked to a molecular bristle. Both presbyopia and cataracts are caused by aggregation of the soluble crystalline lens proteins called the crystallins.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.