Methods and compositions associated with the granulocyte colony-stimulating factor receptor

US10736875B2 · kind B2 · utility

Assignee

• Ligand Pharmaceuticals Incorporated · US

Inventors

• Lin Zhi · San Diego, US
• Keith Marschke · San Diego, US
• Virginia Heather Sharron Grant · San Diego, US
• Steven L. Roach · San Diego, US
• Yixing Shen · Encinitas, US
• Jason C. Pickens · San Diego, US
• Bijan Pedram · San Diego, US
• Cornelis Arjan Van Oeveren · Carlsbad, US
• Lino Valdez · Carlsbad, US
• Andrew R. Hudson · San Diego, US

Key dates

• Filing date: Sep 10, 2018
• Grant date: Aug 11, 2020
• Expiry date: Sep 10, 2038

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12Q1/66
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Some embodiments include compositions and methods of using or identifying compounds that modulate the activity of the granulocyte colony-stimulating factor receptor (GCFR). Some embodiments include use of compounds to treat certain disorders, such as hematopoietic or neurological disorders.