N-[(heteroaryloxy)propanyl]heteroaryl carboxamides as antagonists of orexin subtype 1 receptor activity

US10738031B2 · kind B2 · utility

Assignee

• Boehringer Ingelheim International GmbH · DE

Inventors

• Doris Riether · Biberach an der Riß, DE
• Marco Ferrara · San Donato Milanese, IT
• Niklas Heine · Eberhardzell, DE
• Uta Friederike Lessel · Maselheim, DE
• Janet Rachel Nicholson · Oberhofen, DE
• Anton Pekcec · Munich, DE

Key dates

• Filing date: Apr 7, 2017
• Grant date: Aug 11, 2020
• Expiry date: Apr 7, 2037

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D413/14
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

This invention relates to compounds of formula (I), a process for their preparation, pharmaceutical compositions containing them and their use in the treatment of conditions having an association with the orexin sub-type 1 receptor. Ar1 and Ar2 have meanings given in the description.