Engineered microcompartment protein and related methods and systems of engineering bacterial systems for non-native protein expression and purification

US10738090B2 · kind B2 · utility

Assignees

• Lawrence Livermore National Security, LLC · US
• The Regents of the University of California · US

Inventors

• Mimi Cho Yung · Milpitas, US
• Timothy S. Carpenter · Livermore, US
• Tek Hyung Lee · Pleasanton, US
• David Savage · Berkeley, US

Key dates

• Filing date: Dec 13, 2018
• Grant date: Aug 11, 2020
• Expiry date: Dec 13, 2038

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2319/70
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

Engineered microcompartment proteins, and related engineered microcompartment, vectors, cells compositions, methods and systems configured to provide within a cell one or more proteins non-native to the cell are described, wherein the one or more proteins non-native to the cell are contained in at least one engineered microcompartment within the cell.