Methods of producing nor-opioid and nal-opioid benzylisoquinoline alkaloids
US10738335B2 · kind B2 · utility
1Cited by
13References
11Claims
0Family size
Assignee
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Key dates
| Filing date | Sep 10, 2018 |
| Grant date | Aug 11, 2020 |
| Priority date | — |
| Expiry date | Sep 10, 2038 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Y305/04016
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A method of demethylizing an opioid to a nor-opioid is provided. The method comprises contacting an opioid with at least one enzyme. Contacting the opioid with the at least one enzyme converts the opioid to a nor-opioid. A method of converting a nor-opioid to a nal-opioid is provided. The method comprises contacting a nor-opioid with at least one enzyme. Contacting the nor-opioid with the at least one enzyme converts the nor-opioid to a nal-opioid.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.