Patent · US Active

Analyzer and analytical method for predicting prognosis of cancer radiotherapy

US10738363B2 · kind B2 · utility

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18Claims
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Key dates

Filing dateAug 30, 2017
Grant dateAug 11, 2020
Priority date
Expiry dateAug 3, 2038

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12Q2600/178
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

The present invention provides an analyzer for predicting a prognosis of cancer radiotherapy, including a detection device and an arithmetic device. In a specimen, expression levels of a plurality of microRNAs (miRNAs) can be detected by the detection device. The miRNAs includes hsa-miR-130a-3p, hsa-miR-215-5p, hsa-miR-29a-3p, hsa-let-7b-5p, hsa-miR-19b-3p, hsa-miR-374a-5p and hsa-miR-148a-3p. The expression levels of miRNAs can be analyzed by the arithmetic device using logistic regression, and the analyzed values can be used to determine that the prognosis of cancer radiotherapy is poor or good.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.