Patent · US Active

Lysin polypeptides active against Gram-negative bacteria

US10744189B2 · kind B2 · utility

5Cited by

1References

14Claims

0Family size

Assignee

CONTRAFECT CORPORATION · US

Inventors

Raymond Schuch · New York, US
Simon Hoffenberg · Hartsdale, US
Michael Wittekind · Bainbridge Island, US

Key dates

Filing date	Sep 16, 2016
Grant date	Aug 18, 2020
Priority date	—
Expiry date	Sep 16, 2036

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY02A50/30
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present disclosure provides methods and compositions useful for the prophylactic and therapeutic amelioration and treatment of infections caused by Gram-negative bacteria, including Pseudomonas aeruginosa. The disclosure further provides compositions and methods of incorporating and utilizing lysin polypeptides of the present disclosure for augmenting the efficacy of antibiotics generally suitable for the treatment of Gram-negative bacterial infection.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.