Patent · US Active

Antibody drug conjugates of kinesin spindel protein (KSP) inhibitors with anti-CD123-antibodies

US10744205B2 · kind B2 · utility

9Cited by

2References

28Claims

0Family size

Assignee

Bayer Pharma Aktiengesellschaft · DE

Inventors

Hans-Georg Lerchen · Leverkusen, DE
Anne-Sophie REBSTOCK · Écully, FR
Yolanda Cancho Grande · Leverkusen, DE
Sven Wittrock · Berlin, DE
Beatrix Stelte-Ludwig · Wülfrath, DE
Christoph MAHLERT · Wuppertal, DE
Simone Greven · Dormagen, DE
Stephan MÄRSCH · Cologne, DE
Dennis KIRCHHOFF · Berlin, DE

Key dates

Filing date	Jun 20, 2016
Grant date	Aug 18, 2020
Priority date	—
Expiry date	Jun 20, 2036

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2317/92
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present application relates to novel binder drug conjugates (ADCs), to active metabolites of these ADCs, to processes for preparing these ADCs, to the use of these ADCs for the treatment and/or prophylaxis of diseases and to the use of these ADCs for preparing medicaments for treatment and/or prophylaxis of diseases, in particular hyperproliferative and/or angiogenic disorders such as, for example, cancer diseases. Such treatments can be effected as monotherapy or else in combination with other medicaments or further therapeutic measures.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.