Fluorescent compounds for imaging of blood vessels and blood flow, and an in vivo screen for pro- and anti-angiogenic agents
US10744213B2 · kind B2 · utility
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3Claims
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Key dates
| Filing date | Feb 14, 2017 |
| Grant date | Aug 18, 2020 |
| Priority date | — |
| Expiry date | May 9, 2038 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61B2503/42
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention discloses fluorescent compounds and a method for their use for selective imaging of blood vessels and blood flow. By applying these fluorescent compounds and the imaging process to a zebrafish model, the present invention further provides methods and procedures for the discovery, selection, and characterization of pro- and anti-angiogenic agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.