Method for preparing 2-amino-N-(2,2,2-trifluoroethyl) acetamide
US10745344B2 · kind B2 · utility
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Key dates
| Filing date | Jan 14, 2019 |
| Grant date | Aug 18, 2020 |
| Priority date | — |
| Expiry date | Jan 14, 2039 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/55
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Disclosed are methods for preparing compounds of Formula 1 and 1A. The first method utilizes a benzyl carbamate amine protecting group and an intermediate of Formula 4. The second method utilizes a tert-butyl carbamate amine protecting group and an intermediate of Formula 7. The third method utilizes a dibenzyl amine protecting group.Also disclosed is a compound, phenylmethyl N-[2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl]carbamate (a compound of Formula 4).Further disclosed is a method for preparing a compound of Formula 14 from a compound of Formula 15 and a compound of Formula 1 or 1A.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.