Patent · US Active

1,3,5-triazine derivative and method of using same

US10745383B2 · kind B2 · utility

1Cited by

1References

15Claims

0Family size

Assignees

Inventors

Na Zhao · Beijing, CN
Shulong Wang · Beijing, CN
Xijie Liu · Beijing, CN
Yuandong Hu · Beijing, CN
Hui Zhang · Jinan, CN
Hong Luo · Clemson, US
Yong Peng · Beijing, CN
Yongxin Han · Kirkland, CA
Xiquan Zhang · 安丰镇, CN
Hongjiang Xu · Lianyungang, CN

Key dates

Filing date	Jul 29, 2016
Grant date	Aug 18, 2020
Priority date	—
Expiry date	Jul 29, 2036

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D401/12
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Disclosed are compounds having formulae I and II or pharmaceutically acceptable salts or hydrates thereof, a preparation method thereof and pharmaceutical compositions thereof. The compounds having formulae I and II possesses an isocitrate dehydrogenase 2 (IDH2) inhibitory activity and are capable of treating IDH2 mutation-induced cancers.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.