Patent · US Active

Antibody fusion protein and related compositions for targeting cancer

US10745478B2 · kind B2 · utility

2Cited by

0References

16Claims

0Family size

Inventors

Rachael Sirianni · San Francisco, US
Rebecca Cook · Scottsdale, US
Tsafrir Mor · Tempe, US
Joseph Blattman · Scottsdale, US

Key dates

Filing date	Feb 17, 2017
Grant date	Aug 18, 2020
Priority date	—
Expiry date	Feb 17, 2037

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2750/12043
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Disclosed herein are compositions comprising a polypeptide with at least two domains, wherein the first domain is capable of binding CD3 and the second domain is capable of binding to a cancer cell. Also disclosed herein are methods of treating cancer in a subject, comprising: providing a composition comprising a polypeptide with at least two domains, wherein the first domain is capable of binding CD3 and the second domain is capable of binding to a cancer cell; and treating the cancer by administering a therapeutically effective dosage of the composition to the subject.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.