Patent · US Active

Automated system for HTP genomic engineering

US10745694B2 · kind B2 · utility

7Cited by

106References

25Claims

0Family size

Assignee

Zymergen Inc. · US

Inventors

Zach Serber · Sausalito, US
Erik Jedediah Dean · Lafayette, US
Shawn Manchester · Oakland, US
Katherine Gora · Berkeley, US
Michael Flashman · Eureka, US
Erin Shellman · Seattle, US
Aaron Kimball · San Francisco, US
Shawn Szyjka · Martinez, US
Barbara Frewen · Alameda, US
Thomas Treynor · Berkeley, US
Kenneth S. Bruno · Walnut Creek, US

Key dates

Filing date	Nov 27, 2019
Grant date	Aug 18, 2020
Priority date	—
Expiry date	Nov 27, 2039

Classification

Technology area (CPC G)Physics
CPC primaryG01N2035/1058
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

The present disclosure provides a HTP microbial genomic engineering platform that is computationally driven and integrates molecular biology, automation, and advanced machine learning protocols. This integrative platform utilizes a suite of HTP molecular tool sets to create HTP genetic design libraries, which are derived from, inter alia, scientific insight and iterative pattern recognition. The HTP genomic engineering platform described herein is microbial strain host agnostic and therefore can be implemented across taxa. Furthermore, the disclosed platform can be implemented to modulate or improve any microbial host parameter of interest.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.