Patent · US Active

RNA with a combination of unmodified and modified nucleotides for protein expression

US10745698B2 · kind B2 · utility

0Cited by

3References

7Claims

0Family size

Assignee

ethris GmbH · DE

Inventors

Carsten Rudolph · Krailling, DE
Michael Kormann · Tübingen, DE

Key dates

Filing date	Aug 28, 2015
Grant date	Aug 18, 2020
Priority date	—
Expiry date	Feb 19, 2037

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2320/50
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention relates to a polyribonucleotide with a sequence that codes a protein or protein fragment, wherein the polyribonucleotide comprises a combination of unmodified and modified nucleotides, wherein 5 to 50% of the uridine nucleotides and 5 to 50% of the cytidin nucleotides are modified uridine nucleotides or modified cytidin nucleotides.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.