Markers for mood disorders
US10745736B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Oct 1, 2015 |
| Grant date | Aug 18, 2020 |
| Priority date | — |
| Expiry date | Oct 1, 2035 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/304
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Disclosed is a method for diagnosing a mood disorder or susceptibility to a mood disorder, including depressive disorders and bipolar disorder, from a biological sample taken from a subject. The method includes detecting markers of monoamine oxidase-A (MAO-A) in the biological sample; determining MAO-A concentration from the markers; and correlating the MAO-A concentration in the biological sample to a control group which does not have a mood disorder in order to diagnose or determine susceptibility to the mood disorder in the subject. Also disclosed is a method of detecting peripheral markers of MAO-A for the diagnosis of a mood disorder or susceptibility to a mood disorder. Also provided are polypeptide markers.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.