System and method for interactive patient specific simulation of radiofrequency ablation therapy
US10748438B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Feb 24, 2014 |
| Grant date | Aug 18, 2020 |
| Priority date | — |
| Expiry date | Sep 8, 2036 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61B2034/107
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
A method and system for interactive patient-specific simulation of liver tumor ablation is disclosed. A patient-specific anatomical model of the liver and circulatory system of the liver is estimated from 3D medical image data of a patient. A computational domain is generated from the patient-specific anatomical model of the liver. Blood flow in the liver and the circulatory system of the liver is simulated based on the patient-specific anatomical model. Heat diffusion due to ablation is simulated based on a virtual ablation probe position and the simulated blood flow in the liver and the circulatory system of the liver by solving a bio-heat equation for each node on the level-set representation using a Lattice-Boltzmann method (LBM) implementation. Cellular necrosis in the liver is computed based on the simulated heat diffusion. Visualizations of a computed necrosis region and temperature maps of the liver are generated. A user input is interactively received to modify the position of the virtual ablation probe, the heat diffusion and cellular necrosis is re-simulated based on the user input, and the visualizations of the computed necrosis region and the temperature maps are updat…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.