Sustained release delivery systems comprising traceless linkers

US10751417B2 · kind B2 · utility

Assignee

• Novartis AG · CH

Inventors

• Christopher M. Adams · Arlington, US
• Myriam APRIL · Cambridge, US
• Tanzina Fazal · Cambridge, US
• Cornelia Forster · Bensalem, US
• Edward Charles Hall · Cambridge, US
• Cameron Chuck-munn Lee · Cambridge, US

Key dates

• Filing date: Apr 19, 2018
• Grant date: Aug 25, 2020
• Expiry date: Apr 19, 2038

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P27/02
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Described herein are drug delivery systems for delivering biologically active agents comprising primary or secondary amines, or a ring nitrogen atom of an azaheteroaryl ring, pharmaceutically acceptable salts thereof, drug delivery reagents related thereto, pharmaceutical compositions comprising the drug delivery systems, and the use of the drug delivery systems as sustained release therapeutics.