Alkylating agent for alkylating target with driver oncogene mutation
US10751421B2 · kind B2 · utility
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17Claims
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Key dates
| Filing date | Apr 8, 2019 |
| Grant date | Aug 25, 2020 |
| Priority date | — |
| Expiry date | Apr 8, 2039 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC08G73/0616
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides a novel alkylating agent specifically binding to the genetic mutation site of a driver oncogene. There are provided are a complex formed by binding an alkylating agent to a pyrrole imidazole polyamide specifically binding to the genetic mutation site of a driver oncogene, a driver oncogene mutation-specific alkylating agent comprising the aforementioned complex, and a pharmaceutical composition comprising the aforementioned complex.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.