Composition stably containing single-stranded nucleic acid molecule that suppresses expression of TGF-β1 gene
US10751426B2 · kind B2 · utility
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14Claims
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Key dates
| Filing date | Oct 28, 2016 |
| Grant date | Aug 25, 2020 |
| Priority date | — |
| Expiry date | Feb 9, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N15/113
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides a composition containing a single-stranded nucleic acid molecule consisting of a nucleotide sequence shown by 5′-AGCAGAGUACACACAGCAUAUACC-P-GGUAUAUGCUGUGUGUACUCUGCUUC-P-G-3′ (SEQ ID NO: 1)(in the sequence, P is a proline derivative linker represented by (I) in the DESCRIPTION) and a buffer, and having the following features:
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.