Spirocyclic containing compounds and pharmaceutical uses thereof
US10752615B2 · kind B2 · utility
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13Claims
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Assignee
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Key dates
| Filing date | Aug 16, 2017 |
| Grant date | Aug 25, 2020 |
| Priority date | — |
| Expiry date | Aug 16, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D471/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a novel family of covalent kinases inhibitors, compounds of this class have been found to have inhibitory activity against members of the TEC kinase family, particularly ITK and/or TXK, BTK, TEC and/or combinations thereof. The present invention is directed to a compound of Formula I or pharmaceutically acceptable salt, solvate, solvates of salt, stereoisomer, tautomer, isotope, prodrug, complex or biologically active metabolite thereof, for use in therapy.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.